Dr. David W. Andrews - Publications Pre 1997

Journal Articles pre 1997

Simonian PL, Grillot DA, Andrews DW, Leber B, Nunez G.

Bax homodimerization is not required for Bax to accelerate chemotherapy-induced cell death.
J Biol Chem. 1996 Dec 13;271(50):32073-7.

[Abstract] [Full Text]

Andrews DW, Johnson AE.

The translocon: more than a hole in the ER membrane?
Trends Biochem Sci. 1996 Oct;21(10):365-9.

[Abstract]

Zhu W, Cowie A, Wasfy GW, Penn LZ, Leber B, Andrews DW.

Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types.
EMBO J. 1996 Aug 15;15(16):4130-41. Neither full text nor pdf file is available.

[Abstract] [PDF]

Tomazin R, Hill AB, Jugovic P, York I, van Endert P, Ploegh HL, Andrews DW, Johnson DC.

Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP.
EMBO J. 1996 Jul 1;15(13):3256-66. Neither full text nor pdf file is available.

[Abstract] [PDF]

Do H, Falcone D, Lin J, Andrews DW, Johnson AE.

The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process.
Cell. 1996 May 3;85(3):369-78.

[Abstract] [Full Text]

Hughes MJ, Andrews DW.

Creation of deletion, insertion and substitution mutations using a single pair of primers and PCR.
Biotechniques. 1996 Feb;20(2):188, 192-6. No abstract available.

[PDF]

Young JC, Andrews DW.

The signal recognition particle receptor alpha subunit assembles co-translationally on the endoplasmic reticulum membrane during an mRNA-encoded translation pause in vitro.
EMBO J. 1996 Jan 2;15(1):172-81.

[Abstract] [PDF]

Johnson, A.E., Liao, S., Lin, J., Hamman, B., Do, H., Cowie, A. and Andrews, D.W.

The environment of nascent secretory and membrane proteins at the ER membrane during translocation and integration. (1995)

Cold Spring Harb Symp Quant Biol. 1995;60:71-82. No abstract available.

[Abstract] [PDF]

Young, J.C., Ursini, J., Legate, K., Miller, J.D., Walter, P. and Andrews, D.W.

An amino-terminal domain containing hydrophobic and hydrophilic sequences binds the signal recognition particle receptor " subunit to the ß subunit on the endoplasmic reticulum membrane.

J Biol Chem. 1995 Jun 30;270(26):15650-7.

[Abstract] [Full Text]

Vassilakos, A., Hughes, M.J.G. and Andrews, D.W.

The 3' untranslated region of bovine preprolactin contains a transferable non-poly A mRNA sequence that prolongs translation.

FEBS Lett. 1995 Feb 13;359(2-3):206-10.

[Abstract] [PDF]

Czarnota, G.J., Andrews, D.W., Farrow, N.A. and Ottensmeyer, F.P.

A structure for the signal-sequence binding protein SRP54:3D reconstruction from STEM images of single molecules.

J Struct Biol. 1994 Jul-Aug;113(1):35-46.

[Abstract] [Full Text]

Hughes, M., Vassilakos, A., Andrews, D.W., Hortelano, G., Belmont, J.W. and Chang, P.L.

Delivery of a secretable adenosine deminase through microcapsules - a novel approach to somatic gene therapy.

Hum Gene Ther. 1994 Dec;5(12):1445-55.

[Abstract] [PDF]

Glover, J.R., Andrews, D.W. and Rachubinski, R.A.

Saccharomyces cerevcisiae peroxisomal thiolase is imported as a dimer by a novel translocation mechanism.

Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10541-5.

[Abstract] [PDF]

York, I.A., Roop, C., Andrews, D.W., Riddell, S.R., Graham, F.L. and Johnson, D.C.

A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes.

Cell. 1994 May 20;77(4):525-35.
[Abstract] [PDF]

Janiak, F., Glover, J.R., Leber, B., Rachubinski, R.A. and Andrews, D.W.

Targeting of passenger protein domains to multiple intracellular membranes

Biochem J. 1994 May 15;300 ( Pt 1):191-9

[Abstract] [PDF]

Janiak, F., Leber, B. and Andrews, D.W.

Assembly of Bcl-2 into microsomal and outer mitochondrial membranes.

J Biol Chem. 1994 Apr 1;269(13):9842-9.

[Abstract] [PDF]

Glover, J.R., Andrews, D.W., Subramani, S., and Rachubinski, R.A.

Mutagenesis of the amino targeting signal of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase reveals conserved amino acids required for import into peroxisomes in vivo.

J Biol Chem. 1994 Mar 11;269(10):7558-63.

[Abstract] [PDF]

Andrews, D.W., Gupta, J. and Abisdris, G.

Evidence that the middle T antigen of polyoma virus interacts with the membrane skeleton.

Mol Cell Biol. 1993 Aug;13(8):4703-13.

[Abstract] [PDF]

Andrews, D.W., Young, J.C., Mirels, L. and Czarnota, G

The role of the N region in signal sequence and signal-anchor function.

J Biol Chem. 1992 Apr 15;267(11):7761-9.

[Abstract] [PDF]

Falcone, D. and Andrews, D.W.

Both the 5' untranslated region and the sequences surrounding the start site contribute to efficient initiation of translation in vitro.

Mol Cell Biol. 1991 May;11(5):2656-64.

[Abstract] [PDF]

Thrift, R.N., Andrews, D.W. and Johnson, A.E.

A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation.

J Cell Biol. 1991 Mar;112(5):809-21.

[Abstract] [PDF]

Andrews, D.W.

Examining Protein Translocation in Cell-Free Systems and Microinjected Xenopus Oocytes.

Biotechniques. 1989 Oct;7(9):960-2, 964-7

[Abstract] [PDF]

Andrews, D.W., Lauffer, L., Walter, P. and Lingappa, V.R.

Evidence for a two step mechanism involved in the assembly of functional signal recognition particle receptors.

J Cell Biol. 1989 Mar;108(3):797-810.

[Abstract] [PDF]

Ottensmeyer, F.P., Andrews, D.W., Arsenault, A.L., Heng, Y.M., Simon, G.T. and Weatherly, G.

Elemental imaging by electron energy loss microscopy.

(1988) Scanning, 10, 227-238.

[PDF]

Andrews, D.W., Perara, E.P., Lesser, C. and Lingappa, V.R..

Sequences beyond the cleavage site influence signal peptide function.

J Biol Chem. 1988 Oct 25;263(30):15791-8.

[Abstract] [PDF]

Rothman, R.E., Andrews, D.W., Calayag, M.C. and Lingappa, V.R.

Construction of defined polytopic integral transmembrane proteins.

J Biol Chem. 1988 Jul 25;263(21):10470-80.

[Abstract] [PDF]

Andrews, D.W., Walter, P. and Ottensmeyer, F.P.

Evidence for an extended 7SL RNA structure in the signal recognition particle.

EMBO J. 1987 Nov;6(11):3471-7.

[Abstract] [PDF]

Mize, N.K., Andrews, D.W. and Lingappa, V.R.

A stop transfer sequence recognizes receptors for nascent chain translocation across the endoplasmic reticulum membrane.

Cell. 1986 Dec 5;47(5):711-9.

[Abstract] [PDF]

Andrews, D.W., Yu, A.H.C. and Ottensmeyer, F.P.

Automatic selection of molecular images from dark field electron micrographs.

Ultramicroscopy, 1986, 19, 1-14.

[Abstract] [PDF]

Andrews, D.W., Walter, P. and Ottensmeyer, F.P.

Structure of the signal recognition particle by electron microscopy. (1985)

Proc Natl Acad Sci USA. 1985 Feb;82(3):785-9.

[Abstract] [PDF]

Harauz, G., Andrews, D.W. and Ottensmeyer, F.P.

Electron microscopic visualization of the side chains of the poly-L-lysine alpha helix.

Ultramicroscopy 1983; 12, 59-64. No abstract available.

[PDF]

Andrews, D.W. and Ottensmeyer, F.P.

Electron microscopy of the Poly-L-lysine alpha helix.

Ultramicroscopy. 1982;9(4):337-48.

[Abstract] [PDF]