L P Billen, A Shamas-Din, D W Andrews

Bid: a Bax-like BH3 protein

Oncogene 27, S93-S104 (30 July 2009)

Galluzzi L. et al. (Andrews, D.W.  of 80 authors).

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

Cell Death and Differentiation. 16, 1093–1107

Le Lam; Xiuying Hu; Zackie Aktary; David W Andrews; Manijeh Pasdar.

Tamoxifen and ICI 182,780 increase Bcl-2 levels and inhibit growth of breast carcinoma cells by modulating PI3K/AKT, ERK and IGF-1R pathways independent of ER? .

Accepted Breast Cancer Research and Treatment November 11, 2008, 10.1007/s10549-008-0231-y

Jonathan F. Lovell, Lieven P. Billen, Scott Bindner, Aisha Shamas-Din, Cecile Fradin, Brian Leber, and David W. Andrews

Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax .

Cell 135(6): 1074-1084, 04 December 2008

Lieven P. Billen, Candis L. Kokoski, Jonathan F. Lovell, Brian Leber, David W. Andrews

Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax

PLoS Biol 6(6): e147 doi:10.1371/journal.pbio.0060147

Wang L, Kong F, Kokoski CL, Andrews DW, Xing C.

Development of dimeric modulators for anti-apoptotic Bcl-2 proteins.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):236-40. Epub 2007 Oct 30.

Criollo, A., Maiuri, M.C., Vitale, I., Fiebig, A, Andrews, D.W., Molgo J., Diaz, J., Lavandero, S., Harper, F., Pierron, G., di Stefano, D., Rizzuto, R., Szabadkai, G., and Kroemer, G., (2007)

Regulation of autophagy by the inositol trisphosphate receptor.

Cell Death and Differentiation 14:1029-1039.

Keita, M., Leblanc, C., Andrews, D.W. and Ramanathanan. S., (2007)

GIMAP5 regulates mitochondrial integrity from a distinct subcellular compartment.

Biochem. Biophys. Res. Comm., 361:481-6.

Satsoura D, Leber B, Andrews DW, Fradin C.

Circumvention of fluorophore photobleaching in fluorescence fluctuation experiments: a beam scanning approach.

 Chemphyschem. (2007) 8:834-48

Henderson, M.P.A., Billen, L.P., Kim, P.K., and Andrews, D.W.

Cell free analysis of tail-anchor protein targeting to membranes

Methods. (2007) 41:427-38.

Leber, B., Lin, J., Andrews, D.W. (2007)

Embedded together: The life and death consequences of interaction of the Bcl-2 family with membranes

Apoptosis 12:897-911.

M.P.A. Henderson, Y.T. Hwang, J.M. Dyer, R.T. Mullen and D.W. Andrews

The C-terminus of cytochrome b5 confers endoplasmic reticulum specificity by preventing spontaneous insertion into membranes.

Biochem Journal (2007). Volume 401. Pages 701-709.

Iain L. Mainprize, Daniel R. Beniac, Elena Falkovskaia, Robert M. Cleverley, Lila M. Gierasch, F. Peter Ottensmeyer, and David W. Andrews

The Structure of Escherichia coli Signal Recognition Particle Revealed by Scanning Transmission Electron Microscopy.

Mol Biol Cell. 2006, 17:5063-74.

Kong, D., Xu, L., Zhu, L., Zhu, W., Andrews, D.W., and Kuo, T.H.,

Suppression of IP3-mediated calcium release and apoptosis by Bcl-2 involves the participation of protein phosphatase 1.

Mol Cell Biochem. 2007, 295:153-65.

Fiebig, A., Hollerbach, C. Leber, B., and Andrews, D.W.

Bcl-XL is ten times more potent and qualitatively different from Bcl-2 at inhibiting apoptosis.

BMC Cancer 6:213

Tan, C., Dlugosz, P.J., Peng, J., Zhang, Z., Lapolla, S.M., Andrews D.W., and Lin, JZ

Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2.

J Biol Chem. 2006 May 26;181:14764-75.

Dlugosz, P.J., Billen, L., Annis, M.G., Zhu, W., Zhang, Z., Lin, J., Leber, B. and Andrews, D.W.

Bcl-2 changes conformation to inhibit Bax oligomerization.

EMBO J. 2006 Jun 7;25:2287-96. 

Annis MG, Soucie EL, Dlugosz PJ, Cruz-Aguado JA, Penn LZ, Leber B, Andrews D.W.

Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis.

EMBO J. 2005 Jun 15;24(12):2096-103. 

Dejuan Kong, Liping Xu, Yingjie Yu, Weijia Zhu, David W. Andrews, Yisang Yoon and Tuan H. Kuo

Regulation of Ca²⁺-induced permeability transition by Bcl-2 is antagonized by Drp1 and hFis

Molecular and Cellular Biochemistry 272: 187-199, 2005

Hwang YT, Pelitire SM, Henderson MP, Andrews DW, Dyer JM, Mullen RT 

Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondria.

Plant Cell. 2004 Nov;16(11):3002-19.

Zhang Z, Lapolla SM, Annis MG, Truscott M, Roberts GJ, Miao Y, Shao Y, Tan C, Peng J, Johnson AE, Zhang XC, Andrews DW, Lin J.

Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax.

J Biol Chem. 2004 Oct 15;279(42):43920-8.

Kim PK¹, Annis MG¹, Dlugosz PJ, Leber B, Andrews DW. (2004)

During apoptosis bcl-2 changes membrane topology at both the endoplasmic reticulum and mitochondria. 

Mol Cell. 2004 May 21;14(4):523-9. ¹Co-authors.

McCartney, A., Dyer , J., Dhanoa, P., Kim, P.K., Andrews, D.W. and Mullen, R.(2004)

Membrane-bound fatty acid desaturases are inserted cotranslationally into the ER and contain different ER retrieval motifs at their carboxy termini.  

The Plant Journal (2004) 37, 156-173. 

Annis, M.G., Yethon, J.A., Leber, B. and Andrews, D.W. (2003)

There is more to life and death than mitochondria: Bcl-2 Proteins at the Endoplasmic Reticulum. 

Biochim Biophys Acta. 2004 Mar 1;1644(2-3):115-23.

Xue, L-Y., Chiu, S-M., Fiebig, A., Andrews, D.W. and Oleinick, N. L.   

Photodamage to Multiple Bcl-xL Isoforms by Photodynamic Therapy with the Phthalocyanine Photosensitizer Pc 4.

Oncogene. 2003 Dec 18;22(58):9197-204.

Yethon, J.A.Epand, R.F., Leber, B., Epand, R.M. and Andrews, D.W.  

Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis.

J Biol Chem. 2003 Dec 5;278(49):48935-41.   

Janumyan, Y.M., Greider, C., Chattopadhyay, A., Cheng ,N., Soucie, E.L., Penn L.Z., Andrews, D.W., Knudson, C.M. and Yang, E.

Bcl-XLand Bcl-2 coordinately regulate apoptosis, cell cycle arrest, and cell cycle entry. 

EMBO J. 2003 Oct 15;22(20):5459-70.

Legate, K.R. and Andrews, D.W.  

The b-subunit of the SRP receptor is a novel GTP binding protein without intrinsic GTPase activity. (2003) 

J Biol Chem. 2003 Jul 25;278(30):27712-20.  

Andrews, D.W

Protein origami for beginners. 

Dev Cell. 2002 Nov;3(5):608-10. Review.  

Legate KR, Andrews DW.

Assembly strategies and GTPase regulation of the eukaryotic and Escherichia coil translocons.

Biochem Cell Biol. 2001;79(5):593-601.

Zhu W, Leber B, Andrews DW.

Cytoplasmic O-glycosylation prevents cell surface transport of E-cadherin during apoptosis.

EMBO J. 2001 Nov 1;20(21):5999-6007.   

Soucie EL, Annis MG, Sedivy J, Filmus J, Leber B, Andrews DW, Penn LZ.

Myc potentiates apoptosis by stimulating Bax activity at the mitochondria.

Mol Cell Biol. 2001 Jul;21(14):4725-36.  

Annis MG, Zamzami N, Zhu W, Penn LZ, Kroemer G, Leber B, Andrews DW.

Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event.

Oncogene. 2001 Apr 12;20(16):1939-52.

Millman JS, Qi HY, Vulcu F, Bernstein HD, Andrews DW.

FtsY binds to the Escherichia coli inner membrane via interactions with phosphatidylethanolamine and membrane proteins.

J Biol Chem. 2001 Jul 13;276(28):25982-9. 

Soltys, B.J., Andrews, D.W., Jemmerson, R., and Gupta, R.S.

Cytochrome-C localizes in secretory granules in pancreas and anterior pituitary.

Cell Biol Int. 2001;25(4):331-8.  

Legate KR, Falcone D, Andrews DW.  

Nucleotide-dependent binding of the GTPase domain of the signal recognition particle receptor beta-subunit to the alpha-subunit.

J Biol Chem. 2000 Sep 1;275(35):27439-46.

Andrews DW.

Transport across membranes: a question of navigation.

Cell. 2000 Jul 21;102(2):139-44.

Daugas, E., Susin, S.A., Zamzami, N., Ferri, K., Larochette, N., Prévost, Leber, B., Andrews, D.W., Irinopoulou, T., Bruneval, P., Penninger, J. And Kroemer, G.

Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. 

FASEB J. 2000 Apr;14(5):729-39.  

Brenner, C., Cadiou, H., Vieira, H.L.A., Zamzami, N., Marzo, I., Xie, Z., Leber, B., Andrews, D.W., Duclohier, H., Reed, J.C., and Kroemer, G.

Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator.

Oncogene. 2000 Jan 20;19(3):329-36  

Kim PK, Hollerbach C, Trimble WS, Leber B, Andrews DW.

Identification of the endoplasmic reticulum targeting signal in vesicle-associated membrane proteins.

J Biol Chem. 1999 Dec 24;274(52):36876-82.

Falcone D, Do H, Johnson AE, Andrews DW.

Negatively charged residues in the IgM stop-transfer effector sequence regulate transmembrane polypeptide integration.  

J Biol Chem. 1999 Nov 19;274(47):33661-70.

Millman JS, Andrews DW.

A site-specific, membrane-dependent cleavage event defines the membrane binding domain of FtsY.

J Biol Chem. 1999 Nov 19;274(47):33227-34.

Thangaraju M, Sharma K, Leber B, Andrews DW, Shen SH, Srikant CB.

Regulation of acidification and apoptosis by SHP-1 and Bcl-2.

J Biol Chem. 1999 Oct 8;274(41):29549-57.  

Lee ST, Hoeflich KP, Wasfy GW, Woodgett JR, Leber B, Andrews DW, Hedley DW, Penn LZ.

Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts.

Oncogene. 1999 Jun 10;18(23):3520-8.  

Froesch, B.A., Aimé-Sempé, C., Leber, B., Andrews, D.W. and Reed, J.C.

Inhibition of p53 transcriptional activity by Bcl-2 requires its membrane-anchoring domain. (1999)

J Biol Chem. 1999 Mar 5;274(10):6469-75  

Zhu W, Eicher A, Leber B, Andrews DW.

At the onset of transformation polyomavirus middle-T recruits shc and src to a perinuclear compartment coincident with condensation of endosomes.

Oncogene. 1998 Aug 6;17(5):565-76.  

Thomsen L, Robinson TL, Lee JC, Farraway LA, Hughes MJ, Andrews DW, Huizinga JD.

Interstitial cells of Cajal generate a rhythmic pacemaker current.

Nat Med. 1998 Jul;4(7):848-51. 

Hughes MJ, Andrews DW.

A single nucleotide is a sufficient 5' untranslated region for translation in an eukaryotic in vitro system.

FEBS Lett. 1997 Sep 1;414(1):19-22.  

Kim PK, Janiak-Spens F, Trimble WS, Leber B, Andrews DW. 

Evidence for multiple mechanisms for membrane binding and integration via carboxyl-terminal insertion sequences.

Biochemistry. 1997 Jul 22;36(29):8873-82. 

Millman JS, Andrews DW.

Switching the model: a concerted mechanism for GTPases in protein targeting.

Cell. 1997 May 30;89(5):673-6. Review.